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London, Smartphones can be used to make high-resolution movies of living cells, without the need for expensive equipment, a new study has found.
Live imaging is a very powerful tool for the study of cells, to learn about how cells respond to different treatments such as drugs or toxins.
However, microscopes and equipment for live imaging are often very expensive.
The new study by researchers at Uppsala University in Sweden makes it possible for laboratories around the world to do the same thing
In the study, old standard inverted microscopes that are very abundant at universities and hospitals were upgraded to high quality live imaging stations using a few 3D-printed parts, off-the-shelf electronics, and a smartphone.
It was shown that the resultant upgraded systems provided excellent cell culture conditions and enabled high-resolution imaging of living cells.
“What we have done in this project is not rocket science, but it shows you how 3D-printing will transform the way scientists work around the world,” said Johan Kreuger, senior lecturer at the Department of Medical Cell Biology at Uppsala University.
“3D-printing has the potential to give researchers with limited funding access to research methods that were previously too expensive,” Kreuger said.
“The technology presented here can readily be adapted and modified according to the specific need of researchers, at a low cost.
“Indeed, in the future, it will be much more common that scientists create and modify their own research equipment, and this should greatly propel technology development,” he added. The study was published in the journal PLOS ONE.
